Graduation in 1981 thrust Guilloume into the world of professional art where he was immediately confronted by a challenging and highly competitive art market. In order to compete, indeed survive, the business-minded Guilloume tapped his creative abilities and established his independence by opening a small custom frame shop which he also used as a gallery to promote his work. Simultaneously, he began saving his pesos for a move to the US where most of his family was residing. In October 1984, he met Gladys Margarita Franco. After a whirlwind romance, they married the following February and moved to Los Angeles in August 1985. Adapting to their new lives in a seemingly enormous city while learning a new language was difficult, but later proved to be rewarding. Guilloume’s first two exhibitions in local Los Angeles galleries (1989 and 1990) were highly successful.


It only took a few years of learning the new culture for Guilloume to decide he wanted to find another American landscape for his family and his work. A friend from Texas told him about Santa Fe, “the city different.” During a short trip to New Mexico, Guilloume fell in love with the colors, the richness of all he saw, and the Land of Enchantment sunsets. He sensed the energy of the Santa Fe society of artists, and he also felt it was an ideal place to raise his young family. By 1992, the family was complete. Gladys and Guilloume had three wonderful young boys and a new baby girl. They rented a U-Haul and off they went to their newly chosen home in Sandia Park on the eastern slope of New Mexico’s Sandia Mountains not far from Albuquerque and Santa Fe. It was there that Guilloume later built his studio in the backyard of their home and began his new body of work called, People Different.


Soon after the move, Guilloume joined various art associations in New Mexico and Arizona. A year later he was showing his work with the Santa Fe Society of Artists in the spring and summer and in Arizona galleries in the fall and winter. Based on the instant popularity of his work, Guilloume began a two-year apprenticeship with local artist, Ralph Roybal so that he could learn the lost wax technique of bronze sculpture creation. Roybal taught Guilloume everything he needed to know from mold making, dressing the wax, and welding, to metal chasing and patina work. In his own words, Guilloume says, "The 90's represent a time of creative retooling for me. That is why I sometimes refer to the 90’s as my “renewal period." It was not long before Guilloume was showing his bronze sculptures in a number of well-established galleries across the US, Canada, and Europe.


The new century came with new opportunities for Guilloume in the way of more acceptance of his art work and in 2002, he was an invited artist at the esteemed Biennale Internazionale Dell’Arte Contemporanea in Florence, Italy. His increased success led to more personal appearances at galleries, museums and art shows in Arizona, Arkansas, California, Nevada, Utah, Oklahoma, Texas, Missouri, South Carolina, Florida, and Washington. During his travels around the country, collectors urged Guilloume to write background narratives for several of his art pieces. And while visiting museums and galleries around the world, Guilloume was encouraged by curators and gallery owners to publish books about his sculptures and paintings. In response, Guilloume—Sculptures and Paintings was printed and released in 2003, Guilloume—Sketches was published in 2007, and Forever: Bronze Reliefs was issued in 2008. A feature story on Guilloume and his bronze work can be found in Sculptural Pursuit Artistic Expressions Magazine (Spring 2008) as a result of Guilloume being named second place winner in the Fourth Annual Art Literary Competition for his bronze relief, People of Silence.


Two themes stand out in Guilloume's work—partnership and family. His message is simple: As human beings, we have more in common than we have differences. He illustrates this message in the universal language of art by creating a beauty that speaks to people from all corners of the earth, from all walks of life, from all political spectra, and from all age groups in his unique and passionate style.